List of chemotherapeutic agents

This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy agent for polychemotherapy (combination chemotherapy). For example, the CHOP regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone.

Besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). Those agents are described in the relevant articles.

Alkylating agents

Altretamine
Bendamustine
Busulfan
Carboquone
Carmustine
Chlorambucil
Chlormethine
Chlorozotocin
Cyclophosphamide
Dacarbazine
Fotemustine
Ifosfamide
Lomustine
Melphalan
Melphalan flufenamide
Mitobronitol
Nimustine
Nitrosoureas
Pipobroman
Ranimustine
Semustine
Streptozotocin
Temozolomide
Thiotepa
Treosulfan
Triaziquone
Triethylenemelamine
Trofosfamide
Uramustine

Anthracyclines

Aclarubicin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mitoxantrone
Pirarubicin
Valrubicin
Zorubicin

Cytoskeletal disruptors (taxanes)

Abraxane
Cabazitaxel
Docetaxel
Larotaxel
Paclitaxel
Taxotere
Tesetaxel

Epothilones

Ixabepilone

Histone deacetylase inhibitors

Entinostat
Romidepsin
Vorinostat
Zabadinostat

Inhibitors of topoisomerase I

Belotecan
Camptothecin
Exatecan
Gimatecan
Irinotecan
Topotecan

Inhibitors of topoisomerase II

Etoposide
Teniposide
Tafluposide

Kinase inhibitors

Bortezomib
Erlotinib
Gefitinib
Imatinib
Vemurafenib
Vismodegib

Nucleotide analogs and precursor analogs

Azacitidine
Azathioprine
Capecitabine
Cladribine
Clofarabine
Cytarabine
Decitabine
Doxifluridine
Fludarabine
Fluorouracil
Gemcitabine
Hydroxyurea
Mercaptopurine
Methotrexate
Nelarabine
Pemetrexed
Tioguanine (formerly Thioguanine)

Peptide antibiotics

Actinomycin
Bleomycin

Platinum-based agents

Carboplatin
Cisplatin
Dicycloplatin
Oxaliplatin
Nedaplatin
Satraplatin

Retinoids

Alitretinoin
Bexarotene
Tretinoin

Vinca alkaloids and derivatives

Vinblastine
Vincristine
Vindesine
Vinorelbine

Full alphabetical listing

Abraxane
Actinomycin
Alitretinoin
All-trans retinoic acid
Altretamine
Azacitidine
Azathioprine
Belotecan
Bendamustine
Bexarotene
Bleomycin
Bortezomib
Busulfan
Cabazitaxel
Camptothecin
Carboplatin
Carboquone
Carmustine
Capecitabine
Cisplatin
Chlorambucil
Chlormethine
Chlorozotocin
Cladribine
Clofarabine
Cyclophosphamide
Cytarabine
Dacarbazine
Daunorubicin
Decitabine
Docetaxel
Doxifluridine
Doxorubicin
Epirubicin
Epothilone
Erlotinib
Etoposide
Exatecan
Fludarabine
Fluorouracil
Fotemustine
Gefitinib
Gemcitabine
Gimatecan
Hydroxyurea
Idarubicin
Ifosfamide
Imatinib
Irinotecan
Ixabepilone
Larotaxel
Lomustine
Melphalan
Melphalan flufenamide
Mercaptopurine
Methotrexate
Mitobronitol
Mitomycin C
Mitoxantrone
Nelarabine
Nimustine
Nitrosoureas
Oxaliplatin
Paclitaxel
Pemetrexed
Pipobroman
Ranimustine
Romidepsin
Semustine
Streptozotocin
Tafluposide
Taxotere
Temozolomide
Tesetaxel
Teniposide
Thiotepa
Tioguanine
Topotecan
Treosulfan
Tretinoin
Triaziquone
Triethylenemelamine
Valrubicin
Vemurafenib
Vinblastine
Vincristine
Vindesine
Vinorelbine
Vismodegib
Vorinostat