Fluroxene

Fluroxene (INN, USAN; brand name Fluoromar), or 2,2,2-trifluoroethyl vinyl ether, is a volatile, inhalational anesthetic. It was synthesized in 1951, and was introduced for clinical use in 1954, but was voluntarily withdrawn from the market in 1974 due to its potential flammability and accumulating evidence that it could cause organ toxicity. In any case, prior to being discontinued, it had largely been superseded by halothane. Fluroxene is metabolized to 2,2,2-trifluoroethanol, a compound responsible for some of the toxicity seen with fluroxene use.

Fluroxene
Clinical data
ATC code
  • None
Identifiers
IUPAC name
  • (2,2,2-trifluoroethoxy)ethene
CAS Number
  • 406-90-6
PubChem CID
  • 9844
ChemSpider
  • 9461
UNII
  • FO7JHA3G03
CompTox Dashboard (EPA)
  • DTXSID5059957
ECHA InfoCard100.006.344
Chemical and physical data
FormulaC4H5F3O
Molar mass126.078 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • C=COCC(F)(F)F
InChI
  • InChI=1S/C4H5F3O/c1-2-8-3-4(5,6)7/h2H,1,3H2
  • Key:DLEGDLSLRSOURQ-UHFFFAOYSA-N

See also

  • Divinyl ether

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